Simply Oncology
Welcome to Simply Oncology.
Cancer is daunting for both patients and for clinical teams.
Dr John McGrane and Dr Michael Rowe are oncologists who want to break down the complex parts of cancer care into clear and simple sessions.
We will dive deep into the world of cancer research, patient stories and the latest cancer breakthroughs.
Simply Oncology will have patient focused episodes along with episodes that allow anyone with an interest in oncology to stay up to date.
We hope you join us as we unpick all parts of cancer.
John & Mike
Simply Oncology
Episode 8: In the Clinic - Cervical cancer: Discussing the KEYNOTE A-18 trial with Dr Gemma Eminowicz
In this episode we look at the KEYNOTE A-18 trial in cervical cancer with Dr Gemma Eminowicz.
This trial was presented by Dr Domenica Lorusso at ESMO 2023 and published in The Lancet in March 2024.
https://doi.org/10.1016/S0140-6736(24)00317-9
This trial took a high-risk group of patients receiving chemoradiation for cervical cancer and they were randomised to placebo vs 2 years of pembrolizumab.
The 2 year follow up results showed progression free survival benefit of 11% in favour of 2 years of pembrolizumab (68% vs 57 %) with a Hazard Ratio of 0.7.
Now we have 2 major trials (KEYNOTE A-18 and INTERLACE) in this chemoradiation space for cervical cancer we look at the similarities and differences between the trials.
Where does this point to our new standard of care in cervical cancer?
We hope you enjoy
John & Mike
(ENGOT-cx11/GOG-3047/KEYNOTE-A18)
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